Andrew Shedlock

College of Charleston

Address: Hollings Marine Lab H212C, 331 Ft Johnson Rd., Charleston, SC 29412
Phone: 843.460.9897
Personal Website:


Ph.D., 1997, University of Washington
M.S., 1992, University of Washington
B.S., 1987, Cornell University

Research Interests

  • Comparative evolutionary genomics; impacts of mobile DNA and non-coding RNA on eukaryotic genome structure and transcriptome function. Computational biology. Phylogeny, ecology and population genetics of marine vertebrates.

Current research projects

  • Annotation, assembly and evolutionary synthesis of DNA repeats for NIH-sponsored amniote genome projects
  • Phylogenetic reconstruction of ancestral vertebrate genome structure
  • RNA-seq of tissue-specific gene expression in marine vertebrates
  • de novo and reference-based transcriptome assembly of marine vertebrates
  • Conservation genetics and molecular ecology of legally protected and commercially important marine species


  • Shaffer, H. B, P. Minx, D. E. Warren, A. M. Shedlock, R. C. Thomson, N. Valenzuela, J. Abrahamian, C. T. Amemiya, et al. 2013. The Western Painted Turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage. Genome Biology 14:R28 doi:10.1186/gb-2013-14-3-r28.
  • Alfoldi, J., F. DiPalma, M. Grabherr, C. Williams, L. Kong, E. Mauceli, P. Russell., C. Lowe, R. Glor, J. D. Jaffe, D. Ray,  A. M. Shedlock, et al.  2011.  The green anole lizard genome:  the first reptilian genome and a comparative analysis with birds and mammals.  Nature 477:587-591.
  • Shedlock, A. M., C. W. Botka, S. Zhao, J. Shetty,T. Zhang, J. S. Liu, P. J. Deschavanne, and S. V. Edwards. 2007. Phylogenomics of non-avian reptiles and the structure of the ancestral amniote genome. Proc. Natl. Acad. Sci. USA. 104:2767-2772.
  • Organ, C. L., A. M. Shedlock, A. Meade, M. Pagel, and S. V. Edwards.  2007. Origin of avian genome size and structure in nonavian dinosaurs.  Nature 446:180-184.
  • Shedlock, A. M., K. Takahashi, and N. Okada. 2004. SINEs of speciation: tracking lineages with retroposons. Trends in Ecology and Evolution. 19(10): 545-553.

Click here for a complete bibliography of downloadable reprints.